KapMA Kit - Methacrylated Kappa-Carrageenan Kit - Adbioink

Carrageenan is a hydrophilic polymer extracted from algae and is used as a gelling agent and emulsifying agent. Among different types of carrageenan, Kappa-carrageenan (κCA), a natural linear water-soluble polysaccharide with one sulphated group per disaccharide (25 to 30% ester sulfate content), is one of the appropriate biomaterial in tissue engineering.  κCa has been seen as a potential candidate for this area in injectable form, due to its gelation properties, mechanical strength and resemblance to chondroitin-4-sulfate anddermatan sulfate, which are the major components of native extracellular matrices (ECM) called glycosaminoglycans (GAGs). κCar is a thixotropic polymer and can be converted into hydrogel form via ionic crosslinking method. However, these crosslinking methods offer hydrogels that have low stability in physiologic conditions. In order to overcome this drawback, κCA is methacrylating to synthesis KapMA with photopolymerization potential. κ-CA has a characteristic of tunable viscosity depending on concentration, temperature, the presence of ions and molecular weight and has properties of high strength, nontoxic and cellular compatibility. As its shear-thinning and thermo-reversible properties are suitable for bioinks, κ-CA could been chosen as a bioink material for 3D extrusion-based bioprinting.

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Microwave assisted methacrylation of Kappa carrageenan: A bioink for cartilage tissue engineering - ScienceDirect

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Microwave assisted methacrylation of Kappa carrageenan: A bioink for cartilage tissue engineering - ScienceDirect

Microwave assisted methacrylation of Kappa carrageenan: A bioink for cartilage tissue engineering - ScienceDirect

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Three-dimensional (3D) bioprinting technologies are a tool used to obtain functional human tissues and organs used for regenerative medicine or drug

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Three-dimensional (3D) bioprinting technologies are a tool used to obtain functional human tissues and organs used for regenerative medicine or drug

BioPen-X (Handheld Bioprinter)